HOW TO APPLY YOUR RETINOL SERUM AT NIGHT
Applying a retinol serum at night is the single most effective way to fight visible signs of ageing - but only if you do it correctly.
In this tutorial, Suzi shows you step-by-step how to apply Dermalistβs Age Defying MultiComplex so you get all the benefits of Vitamin A, peptides, and brightening actives without the irritation.
FREQUENTLY ASKED QUESTIONS
Q: How do you apply retinol serum at night?
A: Apply a pea-sized amount to clean, dry skin after cleansing. Follow with a hydrating serum or moisturiser to minimise dryness.
Q: Should I use retinol every night?
A: If youβre new to retinol, start 2β3 times per week and build up to nightly use as your skin adjusts.
Q: Can I use retinol serum with Vitamin C?
A: Yesβuse Vitamin C in the morning and retinol at night for maximum anti-ageing benefits.
Q: Why is Dermalistβs retinol serum different?
A: It combines Retinal (a potent yet gentle form of Vitamin A) with brightening actives and peptides, making it safe and effective even for sensitive skin.
TRANSCRIPT
Hello! In this session, I want to talk to you about Defy - Dermalistβs Vitamin A serum. Iβll explain how to use it, why itβs important, when to apply it, and what actually happens to your skin when you do.
First things first: Iβve just finished a double cleanse, and Iβm applying Defy at night. Retinol works best in the evening, and Iβll explain why.
What Retinol Does
The retinol in Defy is encapsulated retinol. This means itβs wrapped inside a protective capsule that only releases once it penetrates deeper into the skin. Think of it like a slow-release Panadol - the capsule protects the ingredient until it gets exactly where it needs to go.
This delivery system allows retinol to:
Boost cell turnover (helping smooth wrinkles and refine texture).
Reduce pigmentation and improve tone.
Support collagen and elastin for firmer, plumper skin.
Minimise fine lines and signs of premature ageing.
Because itβs an active ingredient, retinol should be applied at night only, when the skin is in repair mode and away from UV exposure (which can reduce its effectiveness).
Key Supporting Ingredients
Defy isnβt just retinol - itβs a cocktail of anti-ageing actives:
Uplevity Peptide: Think of it like tightening your skinβs βrubber bands.β As we age, collagen and elastin fibres stretch and snap, leading to sagging and crepiness. Uplevity helps restore firmness and elasticity.
Resveratrol + Vitamin C (Stay C 50): Antioxidants that fight free radical damage, pigmentation, and oxidative stress from daily exposure.
Niacinamide (Vitamin B3): Strengthens the barrier, calms redness, and supports skin repair.
Hyaluronic Acid: Attracts and locks in moisture, keeping the skin plump and hydrated.
Together, this blend ensures youβre not just getting Vitamin A, but a complete anti-ageing and skin-supporting treatment.
Application Technique
Start clean: Double cleanse and ensure your skin is fully dry.
Dispense: Pump a small amount (pea-sized for beginners; 1β2 pumps if your skin is tolerant).
Distribute evenly: Tap the serum across your fingertips first, then press lightly over the face. Avoid pumping directly onto one spot, which can overload that area.
Avoid the orbital bone:
Stay clear of the delicate eye contour.
Neck & DΓ©colletage: Add an extra pump if treating these areas.Pro
Tip: Donβt rub too hard. Gentle pressing and light sweeping motions help absorption without causing irritation.
Building Tolerance
If youβre new to retinol, start slow: Use once a week for 2β3 weeks.Then increase to twice per week. Gradually build up to every second night or nightly, depending on how your skin tolerates it. Mild flaking or dryness can occur - thatβs simply old skin cells shedding as new ones are generated.
Pairing Defy with your Dermalist cleanser, exfoliant, and AllSerum will help your barrier adapt more comfortably over time.
Why This Retinol Is Different
Because Defy uses encapsulated retinol alongside soothing niacinamide, hydrating hyaluronic acid, and protective antioxidants, it delivers results deep in the skin without the harsh surface irritation often linked to retinol.
The result? Renewed, firmer, clearer skin that can tolerate Vitamin A long term.
Skincare science, simplified.

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